Stella was born in Kano State into the family of Felix Ebelechukwu and Margaret Modebelu, who are natives of Nnewi in Anambra State. She completed her primary education in 1954 at All Saint Primary School, Onistha, before proceeding to complete her secondary school education in 1964 at Ogidi Girls Secondary School, Ogidi.
She attended University of Bradford where she studied Pharmacy, and graduated in 1969. She later bagged M.Sc certificate in Biopharmaceutical from the University of London, Chelsea College in 1971.
She is an entrepreneur, industrialist and a Pharmacist. She is the founder of Emzor Pharmaceutical Industries Limited, a popular pharmaceutical company that has produced drugs for over 30 years.
Before she established Emzor Pharmaceutical, Stella had worked in several pharmaceutical firms such as Pharma-Deko, Boots the Chemists Limited and Middlesex Hospital, London.
After working in various Pharmaceutical companies and gathered relevant experiences, she started Emzor Chemists Limited as a small retail shop in Shomolu, Lagos, before it later grew to become Emzor Pharmaceutical Industries Ltd in January 1977.
Emzor Pharmaceutical has since grown to become one of the leading pharmaceutical companies in Nigeria with over 50 products since its incorporation.
Dr. Stella Okoli is the fourth richest woman in Nigeria according to 2019 Forbes rating and is worth over $500 million. She came only fourth behind Folorunsho Alakija, Bola Shagaya and Princess Fifi Ekanem Ejindu.